ACTINOBACTERIAL PIGMENT ASSISTED SYNTHESIS OF NANOPARTICLES AND ITS BIOLOGICAL ACTIVITY

Recently, the green synthesis of nanoparticles has gained considerable attention due to its benefits such as cost efficiency, simplicity, eco-friendly nature, biocompatibility and broad applications over conventional chemical physical techniques. In this context twenty actinobacteria were isolated from rhizospheric soil wild carrot screened for their pigment producing ability. These isolates belong genus Streptomyces (58%), followed by Streptosporangium sp. (19%), Nocardia (11%), Actinomadura (8%), Micromonospora (4%). The most promising isolate (NS-05) pink been taken silver nanoparticles. NS-05 was identified based on cultural characteristics 16S rDNA sequence analysis. It closely related with type strain fulvissimus DSM 40593T, S. microflavus NBRC13062T, setonii NRRL ISP-5322T, anulatus RRL B-2000T a similarity 95.6% which shows that it may novel species Streptomyces. bio-pigment assisted synthesized characterized using UV-Vis, FTIR Scanning electron microscopy studies. average size 42.5nm λ max at 433 nm. showed activity against major pathogens like Staphylococcus aureus MTCC 2940, Bacillus subtilis 441 Salmonella typhi, Proteus vulgaris 6380, Escherichia coli 739. findings present research are promising, can also be used other